Peptide research profile

Tesamorelin

Tesamorelin is a synthetic analogue of growth-hormone-releasing hormone (GHRH) that is used clinically for the treatment of HIV-associated lipodystrophy (abnormal fat distribution in individuals with HIV). It is also being researched for its potential to improve peripheral nerve health and slow the progression of mild cognitive impairment while reducing fat mass.

  • Growth hormone signaling
Source review pending1 links under reviewEducational context

Dosing literacy

Dosing & scaling, explained

The moderated mass amounts below are retained for comparison. Near-duplicates, mix-dependent volumes and device markings are excluded. This is educational source context—not a protocol or recommendation.

Recorded amount context

Mass amounts available for comparison

  1. Lower range500 mcg
    Dose

    Recorded example with no verified study backing; shown for amount literacy only.

  2. Mid range2000 mcg
    Dose

    Recorded example with no verified study backing; shown for amount literacy only.

Only mcg or mg amounts are retained. The calculator derives mL, syringe units or pen clicks from the current vial strength, water volume and device.

Schedule literacy

No independently verified schedule

Evidence context

No clinical amount or schedule is inferred from this material. Source verification is pending, and every displayed amount remains educational context rather than guidance.

Research best practices

Storage, handling and interpretation

Product identity

Verify the exact compound, formulation and amount against the product label or certificate before calculation.

Storage & handling

Follow the product label, certificate and validated laboratory SOP; no universal storage assumption is applied here.

Prepared solutions

Label concentration and preparation date, use sterile technique where applicable, and follow a validated stability protocol.

Research orientation

What researchers are exploring

These themes organize the educational information currently available. Individual claims remain under source review and are not treatment claims.

  • 01

    Research on Tesamorelin

    Tesamorelin: An Analogue of GHRH Tesamorelin is an analogue of growth hormone-releasing hormone (GHRH), and it shares similar effects with GHRH and other GHRH analogues like sermorelin, GRF (1-29), and CJC-1295.…

  • 02

    Conclusion

    Tesamorelin reduces inflammation, lowers cardiovascular risk, and supports healthy growth hormone levels, particularly in HIV patients. It also shows promise in treating peripheral nerve damage and cognitive impairment.

Evidence map

What is known—and what still needs verification

Available context is organized without assigning unsupported study models or evidence grades.

  • Source review pending

    Research on Tesamorelin

    Tesamorelin: An Analogue of GHRH Tesamorelin is an analogue of growth hormone-releasing hormone (GHRH), and it shares similar effects with GHRH and other GHRH analogues like sermorelin, GRF (1-29), and CJC-1295.…

  • Source review pending

    Conclusion

    Tesamorelin reduces inflammation, lowers cardiovascular risk, and supports healthy growth hormone levels, particularly in HIV patients. It also shows promise in treating peripheral nerve damage and cognitive impairment.

Recorded protocol library

Amounts recorded for Tesamorelin

These amount records are independent from vial strength, reconstitution volume and measuring device. A recorded source is not the same as study backing, and these values are not recommendations.

  • 01

    Dose · lower endpoint

    500 mcg

    Sign in for schedule, duration and source context.

  • 02

    Dose · upper endpoint

    2000 mcg

    Sign in for schedule, duration and source context.

Technical reference

Identity, limitations and unknowns

Molecular profile

Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu
Molecular Formula
C223H370N72O69S
Molecular Weight
5195.908 g/mol
PubChem CID
44147413
CAS Number
901758-09-6

Important limitations

  • Individual claims and source links have not yet completed editorial verification.
  • Evidence level, applicable study model, formulation, route and population remain unassigned.

Source review

1 links awaiting verification

  1. Source link · pmc.ncbi.nlm.nih.govVerification pending · Source review pending